Phase 2 · NCT04881760

A Study of LY3437943 in Participants Who Have Obesity or Are Overweight

A Phase 2 Study of Once-Weekly LY3437943 Compared With Placebo in Participants Who Have Obesity or Are Overweight With Weight-Related Comorbidities

CompletedVerified

Registry record

Trial details

Trial
A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
ClinicalTrials.gov ID
NCT04881760
Indication
Obesity, Overweight
Phase
Phase 2
Study type
Interventional
Sponsor
Eli Lilly and Company
Enrolment
338
Status
Completed
Interventions
Drug: LY3437943; Drug: Placebo
Comparator
Placebo
Eligible ages
18 Years – 75 Years
Locations
28 sites · Puerto Rico, United States
Study start
20 May 2021
Primary completion
16 May 2022
Study completion
22 Nov 2022
View registry record →

Verification

Last verified
4 Sept 2026
Source
ClinicalTrials.gov
Registry last updated
13 Sept 2023

Endpoints

Primary

Mean Percent Change From Baseline in Body Weight

Secondary

Mean Percent Change From Baseline in Body Weight; Percentage of Participants Who Achieve ≥ 5% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 5% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 10% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 10% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 15% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 15% Body Weight Reduction; Mean Change From Baseline in Body Weight; Mean Change From Baseline in Body Weight; Mean Change From Baseline in BMI; Mean Change From Baseline in BMI; Mean Change From Baseline in Waist Circumference; Mean Change From Baseline in Waist Circumference