Phase 2 · NCT04881760

A Study of LY3437943 in Participants Who Have Obesity or Are Overweight

A Phase 2 Study of Once-Weekly LY3437943 Compared With Placebo in Participants Who Have Obesity or Are Overweight With Weight-Related Comorbidities

CompletedVerified
Trial registry record
What this means

The registry describes the study design and status. This label does not mean results have been reported.

Figure / record sourceLast verified 23 Oct 2026

Registry record

Trial details

Trial
A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
ClinicalTrials.gov ID
NCT04881760
Indication
Obesity, Overweight
Phase
Phase 2
Study type
Interventional
Sponsor
Eli Lilly and Company
Enrolment
338
Status
Completed
Interventions
Drug: LY3437943; Drug: Placebo
Comparator
Placebo
Eligible ages
18 Years – 75 Years
Locations
28 sites · Puerto Rico, United States
Study start
20 May 2021
Primary completion
16 May 2022
Study completion
22 Nov 2022
View registry record →

Verification

Last verified
23 Oct 2026
Source
ClinicalTrials.gov
Registry last updated
13 Sept 2023

Endpoints

Primary

Mean Percent Change From Baseline in Body Weight

Secondary

Mean Percent Change From Baseline in Body Weight; Percentage of Participants Who Achieve ≥ 5% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 5% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 10% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 10% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 15% Body Weight Reduction; Percentage of Participants Who Achieve ≥ 15% Body Weight Reduction; Mean Change From Baseline in Body Weight; Mean Change From Baseline in Body Weight; Mean Change From Baseline in BMI; Mean Change From Baseline in BMI; Mean Change From Baseline in Waist Circumference; Mean Change From Baseline in Waist Circumference