Phase 1 · NCT04143802

A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)

A Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3437943 in Patients With Type 2 Diabetes Mellitus

CompletedVerified

Registry record

Trial details

Trial
A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)
ClinicalTrials.gov ID
NCT04143802
Indication
Diabetes Mellitus, Type 2
Phase
Phase 1
Study type
Interventional
Sponsor
Eli Lilly and Company
Enrolment
72
Status
Completed
Interventions
Drug: LY3437943; Drug: Dulaglutide; Drug: Placebo
Comparator
Placebo
Eligible ages
20 Years – 70 Years
Locations
4 sites · United States
Study start
18 Dec 2019
Primary completion
28 Dec 2020
Study completion
28 Dec 2020
View registry record →

Verification

Last verified
4 Sept 2026
Source
ClinicalTrials.gov
Registry last updated
20 Jan 2021

Endpoints

Primary

Number of Participants with One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration

Secondary

Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve of LY3437943; PK: Maximum Concentration (Cmax) of LY3437943; Change from Baseline in Mean Daily Plasma Glucose (PG)